Marina Rodnina

Thursday, 31st August 2017, 01:21
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Position: Director of the Department of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Göttingen.

Address: Max-Planck-Institut für biophysikalische Chemie, Abteilung Physikalische Biochemie, Am Fassberg 11, 37077, Göttingen.

Phone:+49 (0)551-201 2901

Fax:+49 (0)551-201 2905

Home page: go to >>

E-mail: rodnina<AT>mpibpc.mpg.de

1989 Ph.D., Institute of Molecular Biology and Genetics, Academy of Science Ukraine, Kyiv, Ukraine.

Scientific interests:

  • Kinetics of bacterial translation:

    • Ribosome function and dynamics
    • Regulation and fidelity of translation
    • Ribosome-catalyzed reactions
  • Honors and awards:

    • Member of the German Academy of Sciences Leopoldina (2008) 
    • Elected Member of the European Molecular Biology Organization (2004)

Professional membership:

  • German Association for Biochemistry and Molecular Biology 
  • RNA Society 
  • American Biophysical Society 
  • German University Association 
  • American Society for Biochemistry and Molecular Biology

Other professional activities:

  • Panel member of the review board of the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG)
  • Panel member of the PhD fellowship selection committee of the German Academic Exchange Agency (DAAD)
  • Panel member of the ERC Scientific Council
  • Meeting organizer (Ribosome 2010, Orvieto; Translational Control 2009, Heidelberg; RNA Society Meeting 2004, Banff, Canada)

Member of editorial boards:

  • EMBO Journal
  • EMBO Reports
  • RNA
  • HFSP Journal
  • Molecular Biology Russia
  • Regular activity as a referee for the BBSRC, The Wellcome Trust, Swiss and French National Science Foundations, EMBO Fellowships. Referee for Nature, Science, Nature Struct. Mol. Biol., Proc. Natl. Acad. Sci. USA, Cell, Mol. Cell, EMBO J., and other journals.

Selected publications:

  1. Fischer, N., Konevega, A.L., Wintermeyer, W., Rodnina, M.V., Stark, H. (2010) Ribosome dynamics and tRNA movement as visualized by time-resolved electron cryomicroscopy. Nature 466, 329-333.
  2. Milon, P., Konevega, A. L., Gualerzi, C. O., Rodnina, M. C. (2008) Kinetic checkpoint at a late step in translation initiation. Mol. Cell 30, 712-720.
  3. Konevega, A. L., Fischer, N., Semenkov, Y. P., Stark, H., Wintermeyer, W., and Rodnina, M. V. (2007) Spontaneous reverse movement of tRNA-mRNA through the ribosome. Nat. Struct. Mol. Biol. 14, 318-324.
  4. Bieling, P., Beringer, M., Adio, S., and Rodnina, M. V. (2006) Peptide bond formation does not involve acid-base catalysis by ribosomal residues. Nat. Struct. Mol. Biol. 13, 423-428.
  5. Gromadski, K. B., Daviter, T. and Rodnina, M. V. (2006) A uniform response to mismatches in codon-anticodon complexes ensures ribosomal fidelity. Mol. Cell. 21, 369-377.
  6. Diaconu, M., Kothe, U., Schlünzen, F., Fischer, N., Harms, J., Tonevitski, A.G., Stark, H., Rodnina, M. V., and Wahl, M. C. (2005) Structural basis for the function of the ribosomal L7/L12 stalk in factor binding and activation of GTP hydrolysis. Cell 121, 991-1004
  7. Sievers, A., Beringer, M., Rodnina, M.V., and Wolfenden, R. (2004) The ribosome as an entropy trap. Proc. Natl. Acad. Sci USA 101, 7897-7901.
  8. Pape T., Wintermeyer, W., and Rodnina, M.V. (2000) Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nature Struct. Biol.7, 104-107.
  9. Pape T., Wintermeyer, W., and Rodnina, M.V. (1999) Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome. EMBO J. 18, 3800-3807.
  10. Rodnina, M. V., Savelsbergh, A., Katunin, V.I., and Wintermeyer, W. (1997) Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 385, 37-41.