Oleh Stasyk

Monday, 25th September 2017, 02:52
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Position: Senior Scientist, Acting Head of the Department of Cell Signaling, Deputy Director for Science; Institute of Cell Biology NASU.
Address: 14/16 Drahomanov Str., Lviv, 79005, Ukraine
Phone: +380 32 261 21 46
Fax: +380 32 261 21 08
Home page: go to >>
E-mail: stasyk<AT>cellbiol.lviv.ua

1992 B.S., M.S. in Biology, I. Franko National University, Lviv, Ukraine. 

2004 Ph.D. in Cell Biology, Institute of Cell Biology, Lviv, Ukraine. 

Scientific interests: 

  • Nutrient sensing in eukaryotic cells and cell signaling
  • Mechanisms of autophagy and organelle homeostasis
  • Anticancer therapies based on amino acid deprivation

Professional membership: 

  • Ukrainian Society of Cell Biology (Member) 
  • Ukrainian Biochemical Society (Member) 
  • Ukrainian Science Club (Associated member)

Selected publications:

  1. B. Vynnytska-Myronovska, Y. Kurlishchuk, Y. Bobak, C. Dittfeld, L. A. Kunz-Schughart, O. V. Stasyk. (2013) Three-dimensional environment renders cancer cells profoundly less susceptible to a single amino acid starvation. Amino Acids.: 45(5):1221-30.
  2. B. Vynnytska-Myronovska, Y. Bobak, Y. Garbe, C. Dittfeld, O. Stasyk, L.A Kunz-Schughart. (2012) Single amino acid arginine starvation efficiently sensitizes cancer cells to canavanine treatment and irradiation. International Journal of Cancer. 130(9):2164-75.
  3. B. O. Vynnytska, O. M. Mayevska, Y. V. Kurlishchuk, Y. P. Bobak, and O. V. Stasyk. (2011). Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells. Anticancer Drugs (22(2):148-57.
  4. Y. P. Bobak, B. O. Vynnytska, Y. V. Kurlishchuk, A. A. Sibirny, and O. V. Stasyk. (2010). Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes. Cell Biology International 34(11):1085-9.
  5. O. G. Stasyk, M. Maidan, O. V. Stasyk, P. Van Dijck, J. M. Thevelein, and A. A. Sibirny. (2008) Identification of hexose transporter-like sensor HXS1 and functional hexose transporter HXT1 in the methylotrophic yeast Hansenula polymorpha. Eukaryotic Cell. 7(4):735-46.
  6. O. S. Krasovska, O. G. Stasyk, V. O. Nahorny, O. V. Stasyk, N. Granovski, V. A. Kordium, O. F. Vozianov, and A. A. Sibirny. (2007) Glucose-induced production of recombinant proteins in Hansenula polymorpha mutants deficient in catabolite repression. Biotechnology and Bioengineering. 97(4): 858-70.
  7. O. V. Stasyk, O. G. Stasyk, R. D. Mathewson, J.-C. Farré, V. Y. Nazarko, O. S. Krasovska, S. Subramani, J. M. Cregg and A. A. Sibirny. (2006) Atg28, a novel coiled-coil protein involved in autophagic degradation of peroxisomes in the methylotrophic yeast Pichia pastoris. Autophagy2(1), 30-8.
  8. W. A. Dunn, Jr., J. M. Cregg, J. A. K. W. Kiel, I. J. van der Klei, M. Oku, Y. Sakai, A. A. Sibirny, O. V. Stasyk and M. Veenhuis. (2005) Pexophagy: The selective autophagy of Peroxisomes.Autophagy1(2), 75-83 (review).
  9. O. V. Stasyk, O. G. Stasyk, J. Komduur, M. Veenhuis, J. M. Cregg, and A. A. Sibirny. (2004) A hexose transporter homologue controls glucose repression in the methylotrophic yeast Hansenula polymorpha. Journal of Biological Chemistry. 279(9), 8116-25.
  10. O. V. Stasyk, I. J. van der Klei, A. R. Bellu, J. A. K. W. Kiel, S. Shen, J. M. Cregg, and M. Veenhuis. (1999). A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy.Current Genetics 36, 262-9.